Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CHLORP
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Wed, Sat

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Light blue (citrate) or yellow (SPS or ACD solution).

Remarks
Stability

After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days

Reference Interval

Effective February 19, 2013

Child (0 - 11 years)
Adult (12 years and older)
Therapeutic Range 30-80 ng/mL 50-300 ng/mL
Toxic Level Greater than 200 ng/mL Greater than 750 ng/mL

Interpretive Data

Toxic concentrations may cause drowsiness, coma, hypotension, tachycardia and seizures. Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

80342 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
0090870 Chlorpromazine 3471-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Largactil
  • Ormazine
  • Thorazine
  • Thorazine Spansule
Chlorpromazine