Ordering Recommendation

Detect exposure to cannabinoids.

Mnemonic
CANNAB SP
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate). Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years

Reference Interval

Effective August 17, 2015

Drugs Covered Cutoff Concentrations
11-Nor-9-carboxy-THC 5 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Positive cutoff:
5 ng/mL

For medical purposes only; not valid for forensic use.

The drug analyte detected in this assay, 9-carboxy THC, is a metabolite of delta-9-tetrahydrocannabinol (THC).  Detection of 9-carboxy THC suggests use of, or exposure to, a product containing THC.  This test cannot distinguish between prescribed or non-prescribed forms of THC, nor can it distinguish between active or passive use.  The plasma half-life for 9-carboxy THC metabolite is estimated to range from 4-12 hours.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

80349 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
0090671 11-Nor-9-carboxy-THC, S/P, Quant 8170-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 9-Carboxy-THC
  • Cannabinoids
  • Cannabis
  • Dronabinol
  • Marijuana
  • Marinol
  • Pain Management
  • THC
THC Metabolite, Serum or Plasma, Quantitative