Troponin I

0090613
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Critical
Standard

Ordering Recommendation

Recommended test for the diagnosis and management of acute coronary syndrome.

Mnemonic

TNI

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plasma separator tube.

Specimen Preparation

Remove plasma from cells ASAP or within 2 hours of collection. Specimen must be free of particulate matter including fibrin which can interfere with the assay. Avoid transferring material from the white blood cell/platelet layer located just above the red blood cells. Transport 1 mL plasma. (Min: 0.5 mL).  Plasma and serum specimens should not be submitted interchangeably on the same patient with multiple draws.

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 month

Reference Interval

Effective May 21, 2012
0.0-0.03 ng/mL

Interpretive Data

0.03 ng/mL or less: Negative - repeat testing in four to six hours if clinically indicated.
0.04-0.29 ng/mL: Suspicious for myocardial injury. Serial measurements may be necessary to confirm or exclude the diagnosis of acute coronary syndrome.  Repeat testing in four to six hours if indicated.
0.30 ng/mL or greater: Consistent with myocardial injury. Clinical and laboratory correlation recommended.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

84484

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Components

Component Test Code* Component Chart Name LOINC
0090613 Troponin-I 10839-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Troponin inhibitory subnunit
Troponin I