Ordering Recommendation

Detect overdose. Optimize drug therapy and monitor patient adherence.

Mnemonic
THEO
Methodology

Enzyme Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red. Also acceptable: Green (sodium or lithium heparin).

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Lipemic specimens

Remarks

Lipemic specimens may cause an underestimation of Theophylline level

Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Reference Interval

0-5 months: 6.0-12.0 µg/mL
  Toxic: 20.1 µg/mL or greater 

6 months and older: 10.0-20.0 µg/mL
  Toxic: 25.1 µg/mL or greater

Interpretive Data



Compliance Category

FDA

Note

Not recommended for treatment of neonatal apnea.

Hotline History
N/A
CPT Codes

80198

Components
Component Test Code* Component Chart Name LOINC
0090265 Theophylline 4049-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Aminophylline
  • elixophylin
  • Elixophyllin
Theophylline