Theophylline
Ordering Recommendation
Detect overdose. Optimize drug therapy and monitor patient adherence.
New York DOH Approval Status
Specimen Required
Plain red. Also acceptable: Green (sodium heparin).
Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Refrigerated.
Lipemic specimens. Gel separator tubes are not acceptable, regardless of the tube additive.
Lipemic specimens may cause an underestimation of Theophylline level
After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months
Methodology
Enzyme Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
0-5 months: 6.0-12.0 µg/mL
Toxic: 20.1 µg/mL or greater
6 months and older: 10.0-20.0 µg/mL
Toxic: 25.1 µg/mL or greater
Interpretive Data
FDA
Note
Not recommended for treatment of neonatal apnea.
Hotline History
CPT Codes
80198
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090265 | Theophylline | 4049-3 |
Aliases
- Aminophylline
- Elixophylin
- Elixophyllin