Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic

LORAZ

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles)

Reference Interval

Effective November 18, 2013

Dose-Related Range: 50-240 ng/mL - Dose (Adult): 1-10 mg/d
Toxic: Greater than 300 ng/mL

Interpretive Data

Adverse effects may include respiratory depression, sedation, dizziness, weakness and lethargy.

Compliance Category

Standard

Note

Hotline History

N/A

CPT Codes

80346 (Alt code: G0480)

Components

Component Test Code* Component Chart Name LOINC
0090181 Lorazepam 3724-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Ativan
  • ativan blood level
Lorazepam