Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
LAMOT
Methodology

Quantitative Enzyme Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum or plasma separator tubes. Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 7 days; Refrigerated: 1 week; Frozen: 4 weeks

Reference Interval

Effective November 18, 2013

Therapeutic Range:  2.5-15.0 µg/mL
Toxic:                Not well established

Interpretive Data

Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.  Adverse effects may include dizziness, somnolence,  nausea and vomiting.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

80175

Components
Component Test Code* Component Chart Name LOINC
0090177 Lamotrigine 6948-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lamictal
Lamotrigine