Lamotrigine
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
New York DOH Approval Status
Specimen Required
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated.
Serum or plasma separator tubes. Grossly hemolyzed specimens.
After separation from cells: Ambient: 7 days; Refrigerated: 1 week; Frozen: 4 weeks
Methodology
Quantitative Enzyme Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Effective February 22, 2022
Therapeutic Range: 3-15.0 µg/mL
Toxic: Greater than or equal to 20 µg/mL
Interpretive Data
Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function. Adverse effects may include dizziness, somnolence, nausea and vomiting.
FDA
Note
Hotline History
CPT Codes
80175
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090177 | Lamotrigine | 6948-4 |
Aliases
- Lamictal