Procainamide and NAPA

0090151
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Example Reports
Therapeutic
Toxic

Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic

PROC

Methodology

Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain red. Also acceptable: Green (sodium heparin).

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

EDTA plasma. Gray (sodium fluoride/potassium oxalate) or separator tubes or gels.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 6 months

Reference Interval

Test Number
 Components
 Reference Interval
  N-acetylprocainamide (NAPA) 6.0-20.0 µg/mL
Toxic: 35.1 µg/mL or greater
  Procainamide 4.0-10.0 µg/mL
Toxic: 12.1 µg/mL or greater

Interpretive Data

The commonly expected therapeutic range for the sum of NAPA and Procainamide is 5-30 ug/mL. However, the concentration of NAPA is dependent on many factors, including; time of last procainamide dose, mode of administration, concomitant drug therapy, sample condition, time of sample collection and individual variations in absorption, biotransformation, distribution and excretion. Therapeutic ranges are provided only as a guide for interpretation along with other clinical symptoms and patient history.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

80192

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Components

Component Test Code* Component Chart Name LOINC
0090175 N-acetylprocainamide (NAPA) 3834-9
0090235 Procainamide 3982-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • N-Acetyl Procainamide
  • NAPA
  • Pronestyl
Procainamide and NAPA