Ethylene Glycol
Ordering Recommendation
Aid in assessment of the etiology of anion gap acidosis. Determine whether ethylene glycol poisoning exists.
New York DOH Approval Status
Specimen Required
Timing of specimen collection: Dependent on time of exposure - test upon presentation to hospital.
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) When drawing a blood specimen for ethylene glycol testing, use a nonalcohol-based cleanser at the venipuncture site.
Refrigerated.
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
1-4 days
Reference Interval
Effective February 19, 2013
Therapeutic Range | No therapeutic range - Limit of detection 5 mg/dL |
Toxic Level | Greater than 20 mg/dL |
Interpretive Data
Toxic concentrations may cause intoxication, CNS depression, metabolic acidosis, renal damage and hypocalcemia. Ethylene glycol is extremely toxic. Ingestion can be fatal if patients do not receive immediate medical treatment.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
82693
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090110 | Ethylene Glycol | 5646-5 |
Aliases
- Antifreeze
- Ethane-1, 2-Diol