Protriptyline, SP
Ordering Recommendation
Use to optimize dosing and monitor patient adherence.
New York DOH Approval Status
Specimen Required
Timing of specimen collection: Predose (trough) draw at steady-state concentration.
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.5 mL)
Refrigerated.
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
After separation from cells: Ambient: 5 days; Refrigerated: 5 days; Frozen: 6 months
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon, Wed, Fri
Reported
1-7 days
Reference Interval
Therapeutic Range:
70-240 ng/mL
Toxic: > 400 ng/mL
Interpretive Data
Toxic concentrations may cause hypotension, cardiac abnormalities, seizures, and coma.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
80335 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090106 | Protriptyline, SP | 3999-0 |
Aliases
- protriptyline blood level
- Triptil
- Vivactil
- vivactil blood level