Monitor cyanide exposure.
Sun, Tue, Fri
Timing of specimen collection: Dependent on time of exposure - test upon presentation to hospital.
Green (sodium or lithium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA or K3EDTA).
Do not freeze. Transport 4 mL whole blood in original collection container. (Min: 3 mL) Also acceptable: Transfer specimen to an ARUP Standard Transport Tube.
Serum or plasma. Frozen or refrigerated specimens. Clotted or hemolyzed specimens.
Ambient: 72 hours (if tightly capped); Refrigerated: Unacceptable; Frozen: Unacceptable
Effective February 19, 2013
|Non-smokers||Less than 20 µg/dL|
|Smokers||Less than 40 µg/dL|
|Toxic Level||Greater than 100 µg/dL|
Cyanide poisoning can cause hypoxia, dizziness, weakness and mental and motor impairment. Elevated cyanide concentrations rarely indicate toxicity for patients on nitroprusside therapy. Thiocyanate should be monitored in patients on nitroprusside therapy for potential toxicity.
No compliance statements are in use for this test.
No laboratory test is available to assess cyanide toxicity in patients on nitroprusside therapy. However, thiocyanate toxicity may occur with long-term nitroprusside use (longer than 7-14 days with normal renal function and 3-6 days with renal impairment at greater than 2 µg/kg/min infusion rates). Thiocyanate levels may be monitored on an every other day basis to assess potential thiocyanate toxicity and to indicate possible adjustments in dosage. Refer to Thiocyanate, Serum or Plasma (ARUP test code 2011575).
|Component Test Code*||Component Chart Name||LOINC|
- Hydrocyanic acid