Clonazepam

0090055
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High
Normal
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CLON
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration

Collect

Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles).

Reference Interval

Effective November 18, 2013

Dose-Related Range 20-70 ng/mL - Dose (Adult) 1-8 mg/d
Toxic Greater than 80 ng/mL

Interpretive Data

Adverse effects may include drowsiness, headache, fatigue and ataxia.

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

80346 (Alt code: G0480)

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Components
Component Test Code* Component Chart Name LOINC
0090055 Clonazepam 3494-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 340 Clonazepam
  • Clonopin, S
  • Klonopin
  • Klonopin Wafers
  • Nitrazepam
  • Nitrozepane
  • Rivotril
Clonazepam