Optimize drug therapy and monitor patient adherence.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
New York DOH Approval Status
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration
Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles).
Effective November 18, 2013
|Dose-Related Range||20-70 ng/mL - Dose (Adult) 1-8 mg/d|
|Toxic||Greater than 80 ng/mL|
Adverse effects may include drowsiness, headache, fatigue and ataxia.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
80346 (Alt code: G0480)
|Component Test Code*||Component Chart Name||LOINC|
- 340 Clonazepam
- Clonopin, S
- Klonopin Wafers