Ordering Recommendation

Aid in the assessment of acetaminophen toxicity.

Mnemonic
ACET
Methodology

Spectrophotometry

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Specimens collected in separator tubes, sodium fluoride/potassium oxalate, or sodium citrate anticoagulants.

Remarks
Stability

After separation from cells: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 45 days

Reference Interval

10-30 µg/mL

Critical values:
Post 4-hour ingestion: greater than 150 µg/mL
Post 12-hour ingestion: greater than 40 µg/mL

Interpretive Data

Acetaminophen concentrations greater than 150 µg/mL at 4 hours after ingestion and 40 µg/mL at 12 hours after ingestion are often associated with toxicity.

Acetaminophen levels drawn within 4-6 hours after IV administration of a standard loading dose of 150 mg/kg of N-acetyl cysteine may be falsely low due to interference with the assay.

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

80307

Components
Component Test Code* Component Chart Name LOINC
0090001 Acetaminophen 3298-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Datril
  • Tylenol
  • Tylenol level
Acetaminophen