Ordering Recommendation

Use for the quantitative measurement of soluble mesothelin-related peptides (SMRPs) in serum.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum Separator Tube(SST) or Plain Red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 0.2 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature


Unacceptable Conditions

After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 3 months


Quantitative Enzyme-Linked Immunosorbent Assay




1-8 days

Reference Interval

0.0-1.5 nmol/L

Interpretive Data

MESOMARK is an enzyme-linked immunosorbent assay for the quantitative measurement of soluble mesothelin related peptides (SMRP) in serum.  Measurement of SMRP may aid in the management of patients diagnosed with epithelioid or biphasic mesothelioma.  Epidemiologic studies have established exposure to asbestos fibers as the primary cause of malignant mesothelioma.  Results obtained with different assay methods or kits cannot be used interchangeably.  Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0081285 Soluble Mesothelin Related Peptides 41292-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • MESOMARK (Soluble Mesothelin Related Peptides (MESOMARK(R)))
  • Mesothelin
  • SMRP
Soluble Mesothelin Related Peptides (MESOMARK(R))