Ordering Recommendation

Use as a non-specific marker of neuronal damage.

Mnemonic

NSE CSF

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Separate from cells within 1 hour of collection. Transfer 0.5 mL CSF to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Hemolyzed specimens.

Remarks
Stability

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Reference Interval

1.0-7.0 µg/L

Interpretive Data

This test is performed using the CanAg Neuron Specific Enolase Enzyme Immunoassay. Results obtained with different methods or kits cannot be used interchangeably.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86316

Components

Component Test Code* Component Chart Name LOINC
0081226 Neuron Specific Enolase, CSF 47053-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • NSE
Neuron Specific Enolase, CSF