Ordering Recommendation

Use as a non-specific marker of neuronal damage.

Mnemonic
NSE CSF
Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Separate from cells within 1 hour of collection. Transfer 0.5 mL CSF to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Hemolyzed specimens.

Remarks
Stability

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Reference Interval

1.0-7.0 µg/L

Interpretive Data

This test is performed using the CanAg Neuron Specific Enolase Enzyme Immunoassay. Results obtained with different methods or kits cannot be used interchangeably.

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

86316

Components
Component Test Code* Component Chart Name LOINC
0081226 Neuron Specific Enolase, CSF 47053-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • NSE
Neuron Specific Enolase, CSF