Ordering Recommendation

Diagnose and monitor for fatty acid oxidation disorders and organic acidemias. Use in conjunction with urine organic acids and plasma acylcarnitines testing.

Mnemonic
ACYLGLY
Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performed

Wed

Reported

2-13 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 6 mL urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL) Avoid dilute urine when possible.

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks

Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at https://www.aruplab.com/patienthistory or by contacting ARUP Client Services.

Stability

Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 2 weeks

Reference Interval

Reports include age appropriate reference interval.

Test Number
Components
Reference Interval
  Propionylglycine By report
  Isobutyrylglycine By report
  Butyrylglycine By report
  2-Methylbutyrylglycine By report
  Isovalerylglycine By report
  3-Methylcrotonylglycine By report
  Tiglylglycine By report
  Hexanoylglycine By report
  Phenylpropionylglycine By report
  Suberylglycine By report

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

82542

Components
Component Test Code* Component Chart Name LOINC
0081171 Acylglycines, Urine Interpretation 53718-3
0081172 Propionylglycine 24442-6
0081173 Isobutyrylglycine 24439-2
0081174 Butyrylglycine 24437-6
0081175 2-Methylbutyrylglycine 24435-0
0081176 Isovalerylglycine 24440-0
0081177 3-Methylcrotonylglycine 24436-8
0081178 Tiglylglycine 24444-2
0081179 Hexanoylglycine 24438-4
0081180 Phenylpropionylglycine 24441-8
0081181 Suberylglycine 24443-4
3002335 Creatinine, Urine 2161-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • quantiative analysis of urinary acylglycines
  • urinary acylcarnitines
Acylglycines, Quantitative, Urine