Ordering Recommendation

Diagnose and monitor for fatty acid oxidation disorders and organic acidemias. Use in conjunction with urine organic acids and acylglycines testing.

Mnemonic
CARNPAN
Methodology

Tandem Mass Spectrometry

Performed

Tue, Thu, Sat

Reported

2-7 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Green (sodium or lithium heparin). Also acceptable: Plain red.

Specimen Preparation

Separate plasma or serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL) Avoid hemolysis.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Room temperature specimens. Specimens that have been refrigerated for greater than 12 hours. Grossly hemolyzed specimens.

Remarks

Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at https://www.aruplab.com/patienthistory or by contacting ARUP Client Services.

Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 12 hours; Frozen: 1 month

Reference Interval

Reports include age appropriate reference interval and interpretation.

Test Number
Components
Reference Interval
0080068 Carnitine, Free & Total (Includes Carnitine, Esterified)
Age
Carnitine, Free, Serum/Plasma Carnitine, Total, Serum/Plasma Carnitine, Esterified, Serum/Plasma
Carnitine E/F Ratio, Serum/Plasma
1 - 31 days 15 - 55 µmol/L 21 - 83 µmol/L 4 - 29 µmol/L 0.2 - 0.8
32 days-12 months 29 - 61 µmol/L 38 - 73 µmol/L 7 - 24 µmol/L 0.1 - 0.8
13 months - 6 years 25 - 55 µmol/L 35 - 90 µmol/L 4 - 36 µmol/L 0.1 - 0.8
7 years -20 years 22 - 63 µmol/L 31 - 78 µmol/L 3 - 38 µmol/L 0.1 - 0.9
21 years or older 25 - 60 µmol/L 34 - 86 µmol/L 5 - 29 µmol/L 0.1 - 1.0

0040033 Acylcarnitine Quantitative Profile, Plasma Reports include age appropriate reference intervals and interpretation.

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

The concentration of esterified carnitine is derived from a mathematical calculation using free and total carnitine.

Hotline History
N/A
CPT Codes

82017; 82379

Components
Component Test Code* Component Chart Name LOINC
0040029 C5-OH, 3-OH Isovaleryl 39001-3
0040034 Acylcarnitine, Plasma Interpretation 46252-3
0040037 C2, Acetyl 30191-1
0040038 C3, Propionyl 30551-6
0040039 C4, Iso-/Butyryl 51413-3
0040042 C5, Isovaleryl/2Mebutyryl 30531-8
0040046 C5-DC, Glutaryl 30349-5
0040047 C6, Hexanoyl 30358-6
0040049 C8, Octanoyl 30540-9
0040054 C8:1, Octenoyl 30541-7
0040057 C10, Decanoyl 30327-1
0040058 C10:1, Decenoyl 30328-9
0040062 C12, Dodecanoyl 30331-3
0040063 C12:1, Dodecenoyl 30332-1
0040064 C12-OH, 3-OH-Dodecanoyl 30233-1
0040066 C14, Tetradecanoyl 30565-6
0040067 C14:1, Tetradecenoyl 30566-4
0040068 C14:2, Tetradecadienoyl 30564-9
0040069 C14-OH, 3-OH-Tetradecanoyl 30238-0
0040074 C14:1-OH, 3-OH-Tetradecenoyl 30190-3
0040076 C16, Palmitoyl 30356-0
0040077 C16:1, Palmitoleyl 30357-8
0040078 C16-OH, 3-OH-Palmitoyl 30234-9
0040079 C16:1-OH, 3-OH-Palmitoleyl 30235-6
0040087 C18, Stearoyl 30560-7
0040093 C18:1, Oleyl 30542-5
0040094 C18:2, Linoleyl 30534-2
0040097 C18-OH, 3-OH-Stearoyl 35656-8
0040098 C18:1-OH, 3-OH-Oleyl 30312-3
0040101 C18:2-OH, 3-OH-Linoleyl 30237-2
0080066 Carnitine, Free, Serum/Plasma 14286-9
0081108 Carnitine, Total, Serum/Plasma 14288-5
0081291 Carnitine, Esterified, Serum/Plasma 19074-4
0081292 Carnitine E/F Ratio, Serum/Plasma 40869-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • carnitine panel, plasma
  • plasma carnitine panel
Carnitine Panel