Ordering Recommendation

Use for monitoring treatment of patients previously diagnosed with cystinuria. To diagnose or rule out cystinuria, refer to Cystinuria Panel (0081105) or Amino Acids Quantitative by LC-MS/MS, Urine (2009419).

Mnemonic
QNT CYS U
Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performed

Mon-Fri

Reported

3-7 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

24-hour or other timed urine collection. Avoid dilute urine when possible. Refrigerate 24-hour/timed specimens during collection.

Specimen Preparation

Mix urine well. Transfer 4 mL aliquot urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL) Record total volume and collection time interval on transport tube and test request form.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Refrigerated or room temperature specimens.

Remarks

Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (eg, TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site or by contacting ARUP Client Services.

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month

Reference Interval

Effective November 18, 2019

Test Number
Components
Reference Interval
  Cystine, Urine - Quantitative
Age Reference Interval
0-2 months Less than or equal to 870 µmol/g creatinine
3-11 months Less than or equal to 300 µmol/g creatinine
1-2 years Less than or equal to 150 µmol/g creatinine
3-5 years Less than or equal to 125 µmol/g creatinine
6-11 years Less than or equal to 100 µmol/g creatinine
12 years and older Less than or equal to 150 µmol/g creatinine

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

This test is indicated only to monitor patients with cystinuria on therapy.

Hotline History
N/A
CPT Codes

82131

Components
Component Test Code* Component Chart Name LOINC
0081107 Cystine, Urine - Quantitative 56677-8
0081219 Cystine, 24 Hour Urine 2179-0
0081220 Cystine, Urine - per volume 32169-5
3002334 Creatinine, Urine 2161-8
3002356 Hours Collected 81323-8
3002357 Total Volume 19153-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Urine cystine
Cystine Quantitative, Urine