Ordering Recommendation

Assess adrenal androgen production. Preferred test is Dehydroepiandrosterone Sulfate, Serum (0070040).

Mnemonic

17 KETO

Methodology

Quantitative Spectrophotometry

Performed

Mon, Wed, Fri

Reported

1-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

24-hour urine. Refrigerate during collection.

Specimen Preparation

Transfer two 4 mL aliquots from a well-mixed 24-hour urine collection into 2 ARUP Standard Transport Tubes or 2 ARUP Standard Transport Tubes containing 20 mg Sulfamic Acid (ARUP supply #48098) available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at (800) 522-2787. (Min: 3 mL/aliquot) Adequate refrigeration is the most important aspect of specimen preservation.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks

Record total volume and collection time interval on transport tube and test request form.

Stability

Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

Test Number
Components
Reference Interval
  17-Ketosteroids - per 24h
Male
Female
0-11 months: 0.0-1.0 mg/d
1-5 years: 1.0-2.0 mg/d
6-10 years: 1.0-4.4 mg/d
11-12 years: 1.3-8.5 mg/d
13-16 years: 3.4-9.8 mg/d
17-50 years: 5.3-17.6 mg/d
51 years and older: 4.1-12.1 mg/d
0-11 months: 0.0-1.0 mg/d
1-5 years: 1.0-2.0 mg/d
6-10 years: 1.4-3.9 mg/d
11-12 years: 3.8-9.5 mg/d
13-16 years: 4.5-17.1 mg/d
17-50 years: 4.4-14.2 mg/d
51 years and older: 3.2-10.6 mg/d

  17-Ketosteroids - per volume Not available
  Creatinine, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
3-8 years 140-700 140-700
9-12 years 300-1300 300-1300
13-17 years 500-2300 400-1600
18-50 years 1000-2500 700-1600
51-80 years 800-2100 500-1400
81 years and older 600-2000 400-1300

  Creatinine, Urine - per volume

Interpretive Data

Reference intervals for random urine samples (mg/L) are not available.

Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.

Compliance Category

Standard

Note

An alternative and more specific test for adrenal androgen function is Dehydroepiandrosterone Sulfate, Serum (ARUP test code 0070040).

A large number of substances may interfere with this test. Decreases may be caused by carbamazepine, cephaloridine, cephalothin, chlormerodrin, digoxin, glucose, metyrapone, promazine, propoxyphene, reserpine, and others. Increases may be caused by acetone, acetophenide, ascorbic acid, chloramphenicol, chlorothiazide, chlorpromazine, cloxacillin, dexamethasone, erythromycin, ethinamate, etryptamine, methicillin, methyprylon, morphine, oleandomycin, oxacillin, penicillin, phenaglycodol, phenazopyridine, phenothiazine, piperidine, quinidine, secobarbital, spironolactone, and others. 

Hotline History

N/A

CPT Codes

83586

Components

Component Test Code* Component Chart Name LOINC
0020207 Creatinine, Urine - per volume 2161-8
0020208 Creatinine, Urine - per 24h 2162-6
0080190 17-Ketosteroids - per volume 21038-5
0080191 17-Ketosteroids - per 24h 6766-0
0097110 Total Volume 19153-6
0097111 Hours Collected 30211-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

17-Ketosteroids, Urine