Ordering Recommendation
Determine the Fredrickson classification of individuals with hyperlipoproteinemia. Most useful for identifying the Type III phenotype.
Mnemonic
Methodology
Qualitative Electrophoresis/Quantitative Enzymatic Assay/Detergent Solubilization
Performed
Thu
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Patient should be fasting for 12-15 hours.
Serum separator tube or plain red.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Store and ship refrigerated. DO NOT FREEZE.
Refrigerated.
Heparin and frozen samples. Body fluids.
After separation from cells: Ambient: 24 hours; Refrigerated: 7 days; Frozen: Unacceptable
Reference Interval
Also includes Fredrickson classification.
Interpretive Data
An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor. An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.
CHD Risk Factors
+1 Age: Men, 45 years and older
Women, 55 years and older or premature menopause without estrogen therapy
+1 Family history of premature CHD
+1 Current smoking
+1 Hypertension
+1 Diabetes mellitus
+1 Low HDL cholesterol: 39 mg/dL or less
-1 High HDL cholesterol: 60 mg/dL or greater
20 years and older |
Desirable |
Borderline |
Higher Risk |
---|---|---|---|
Total Cholesterol | 199 mg/dL or less | 200-239 mg/dL | 240 mg/dL or greater |
Triglycerides | 149 mg/dL or less | 150-199 mg/dL | 200-499 mg/dL |
HDL Cholesterol | 40 mg/dL or greater (if no CHD) | 39 mg/dL or less | |
LDL Cholesterol | 129 mg/dL or less (99 mg/dL or less if patient has CHD) | 130-159 mg/dL | 160 mg/dL or greater |
Appearance | Clear | ||
VLDL Cholesterol (calculated) | 30 mg/dL or less |
0-19 years |
Desirable |
Borderline |
High Risk |
---|---|---|---|
Total Cholesterol | 169 mg/dL or less | 170-199 mg/dL | 200 mg/dL or greater |
Triglycerides | 149 mg/dL or less | 150-199 mg/dL | 200-499 mg/dL |
HDL Cholesterol | 40 mg/dL or greater | 39 mg/dL or less | |
LDL Cholesterol | 109 mg/dL or less | 110-129 mg/dL | 130 mg/dL or greater |
Appearance | Clear | ||
VLDL Cholesterol (calculated) | 30 mg/dL or less |
FDA
Note
Body fluids are unacceptable and not valid for lipoprotein testing. Suggest Chylomicron Screen, Body Fluid (0098457).
Hotline History
Hotline History
CPT Codes
83700; 80061
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0020031 | Cholesterol, Serum or Plasma | 2093-3 |
0020040 | Triglycerides, Serum or Plasma | 2571-8 |
0020053 | HDL Cholesterol | 2085-9 |
0020257 | LDL Cholesterol, Direct | 18262-6 |
0020550 | VLDL, Calculated | 13458-5 |
0080504 | Lipoprotein Electrophoresis | 20510-4 |
0095038 | Appearance Chemistry | 11158-3 |
Aliases
- Cholesterol, Serum or Plasma
- HDL Cholesterol
- LDL Cholesterol, Direct
- Lipoprotein Electrophoresis
- Triglycerides, Serum or Plasma
- VLDL, Calculated