Ordering Recommendation

Determine the Fredrickson classification of individuals with hyperlipoproteinemia. Most useful for identifying the Type III phenotype.

Mnemonic

LIPOELECT

Methodology

Qualitative Electrophoresis/Quantitative Enzymatic Assay/Detergent Solubilization

Performed

Thu

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Patient should be fasting for 12-15 hours.

Collect

Serum separator tube or plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Store and ship refrigerated. DO NOT FREEZE.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Heparin and frozen samples. Body fluids.

Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 7 days; Frozen: Unacceptable

Reference Interval

Also includes Fredrickson classification.

Interpretive Data

An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor.  An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.

CHD Risk Factors
+1  Age: Men, 45 years and older
     Women, 55 years and older or premature menopause without estrogen therapy
+1 Family history of premature CHD
+1  Current smoking
+1  Hypertension
+1  Diabetes mellitus
+1  Low HDL cholesterol:  39 mg/dL or less
-1  High HDL cholesterol:  60 mg/dL or greater


20 years and older
Desirable
Borderline
Higher Risk
Total Cholesterol 199 mg/dL or less 200-239 mg/dL 240 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater (if no CHD) 39 mg/dL or less
LDL Cholesterol 129 mg/dL or less (99 mg/dL or less if patient has CHD) 130-159 mg/dL 160 mg/dL or greater
Appearance Clear
VLDL Cholesterol (calculated) 30 mg/dL or less

0-19 years
Desirable
Borderline
High Risk
Total Cholesterol 169 mg/dL or less 170-199 mg/dL 200 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater 39 mg/dL or less
LDL Cholesterol 109 mg/dL or less 110-129 mg/dL 130 mg/dL or greater
Appearance Clear
VLDL Cholesterol (calculated) 30 mg/dL or less

Compliance Category

FDA

Note

Body fluids are unacceptable and not valid for lipoprotein testing. Suggest Chylomicron Screen, Body Fluid (0098457).

Hotline History

N/A

CPT Codes

83700; 80061

Components

Component Test Code* Component Chart Name LOINC
0020031 Cholesterol, Serum or Plasma 2093-3
0020040 Triglycerides, Serum or Plasma 2571-8
0020053 HDL Cholesterol 2085-9
0020257 LDL Cholesterol, Direct 18262-6
0020550 VLDL, Calculated 13458-5
0080504 Lipoprotein Electrophoresis 20510-4
0095038 Appearance Chemistry 11158-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Cholesterol, Serum or Plasma
  • HDL Cholesterol
  • LDL Cholesterol, Direct
  • Lipoprotein Electrophoresis
  • Triglycerides, Serum or Plasma
  • VLDL, Calculated
Lipoprotein Electrophoresis