Ordering Recommendation

Determine specific AAT protein variant(s) in individual with decreased concentration of AAT (<90mg/dL).

Mnemonic
A1A PHENO
Methodology

Qualitative Isoelectric Focusing/Immunoturbidimetry

Performed

Sun-Sat

Reported

2-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 3 months; Frozen: 3 months (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0050001 Alpha-1-Antitrypsin Effective November 17, 2014
90-200 mg/dL
  A1A Phenotype By report

Interpretive Data



Compliance Category

FDA

Note

Interpret with caution if the patient has been transfused within the previous 21 days.

Hotline History
N/A
CPT Codes

82104; 82103

Components
Component Test Code* Component Chart Name LOINC
0050001 Alpha-1-Antitrypsin 1825-9
0099005 A1A Phenotype 32769-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • a-1-Antitrypsin, Phenotype
  • A1A Phenotype
  • A1A Phenotyping
  • A1A reflex
  • AAT deficiency
  • AAT Phenotype
  • AAT Phenotyping
  • AAT Reflex
  • Alpha 1 Antitrypsin
  • Antitrypsin
  • Antitrypsin, Phenotype
  • Pi Typing
  • Protease Inhibitor Allo Typing
  • Protease Inhibitor Typing
Alpha-1-Antitrypsin Phenotype (Includes Alpha-1-Antitrypsin)