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Vitamin D, 1, 25-Dihydroxy
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Ordering Recommendation
May be useful for evaluating calcium metabolism in individuals with hypercalcemia or renal failure in addition to Vitamin D, 25-Hydroxy testing. Test is not appropriate for diagnosing vitamin D deficiency or insufficiency.
Mnemonic
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
Specimen Required
Serum separator tube or plain red, lithium heparin or EDTA plasma.
Allow serum separator or plain red tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Storage/Transport Temperature: Refrigerated.
Refrigerated.
Grossly hemolyzed or lipemic specimens.
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 6 months
Reference Interval
19.9-79.3 pg/mL
Interpretive Data
This test is primarily indicated during patient evaluation for hypercalcemia and renal failure. A normal result does not rule out Vitamin D deficiency. The recommended test for diagnosing Vitamin D deficiency is Vitamin D 25-hydroxy.
FDA
Note
Hotline History
CPT Codes
82652
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0080385 | Vitamin D, 1,25-Dihydroxy | 1649-3 |
Aliases
- 1,25-(OH)2-D
- 1,25-Dihydroxy Vitamin D
- 1,25-Dihydroxycholecalciferol
- 1,25-Dihydroxyvitamin D
- 1,25-Dihydroxyvitamin D3
- Calcitriol
- D, 1-25 Dihydroxy, Vitamin
- Vit D 1,25
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