Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
Diagnostic evaluation of patients suspected to have collagen lysyl hydroxylase deficiency (Ehlers-Danlos Syndrome type VIA). May be useful when evaluating bone resorption (eg, osteoporosis). Preferred test for monitoring bone resorption and response to antiresorptive therapy is C-Telopeptide, Beta-Cross-Linked, Serum (0070416).
MnemonicUnique test identifier.
PYD & DPD
MethodologyProcess(es) used to perform the test.
High Performance Liquid Chromatography (HPLC)
PerformedDays of the week the test is performed.
Wed
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
6-14 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
First morning void.
Collect
Urine.
Specimen Preparation
Transfer 8 mL urine to ARUP Standard Transport Tubes. (Min: 4 mL)
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Age
PYR µmol/mol creatinine
DPYR µmol/mol creatinine
DPYR/PYR Ratio
0-11 months
353-560 µmol/mol crt
46-113 µmol/mol crt
0.13-0.20
1-3 years
108-400 µmol/mol crt
19-94 µmol/mol crt
0.18-0.24
4-9 years
117-325 µmol/mol crt
20-75 µmol/mol crt
0.19-0.25
10-14 years
81-267 µmol/mol crt
13-61 µmol/mol crt
0.17-0.27
15-19 years
38-80 µmol/mol crt
10-18 µmol/mol crt
0.20-0.26
20 years and older
20-40 µmol/mol crt
5-11 µmol/mol crt
0.23-0.29
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
Pyridinoline and Deoxypyridinoline excretion follows a circadian rhythm. Reference intervals have been established on first morning void urine samples.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.