Ordering Recommendation

Useful for investigating possible disorders of mitochondrial metabolism, particularly when used in conjunction with CSF lactate.

Mnemonic
PYRU CSF
Methodology

Quantitative Enzymatic

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Patient should be at complete rest.

Collect

CSF.

Specimen Preparation

1) Immediately after CSF is drawn, add exactly 1 mL CSF to a chilled pyruvate collection tube containing 2 mL 8 percent (w/v) perchloric acid (ARUP supply #16567) available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
2) Mix well for 30 seconds then place in an ice bath for 10 minutes.
3) Centrifuge for 10 minutes at 1500 x g.
4) Decant 2 mL supernatant to an ARUP Standard Transport Tube and freeze. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

If less than 1 mL of CSF is added to collection tube, pH of the supernatant will be too low for testing.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 2 days; Frozen: 1 month

Reference Interval

0.060-0.190 mmol/L

Interpretive Data



Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

84210

Components
Component Test Code* Component Chart Name LOINC
0080312 Pyruvic Acid, CSF 14122-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Pyruvate (Pyruvic Acid, CSF)
  • Pyruvic Acid
Pyruvic Acid, CSF