Ordering Recommendation
Useful for investigating possible disorders of mitochondrial metabolism, particularly when used in conjunction with CSF lactate.
Mnemonic
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Patient should be at complete rest.
CSF.
1) Immediately after CSF is drawn, add exactly 1 mL CSF to a chilled pyruvate collection tube containing 2 mL 8 percent (w/v) perchloric acid (ARUP supply #16567) available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
2) Mix well for 30 seconds then place in an ice bath for 10 minutes.
3) Centrifuge for 10 minutes at 1500 x g.
4) Decant 2 mL supernatant to an ARUP Standard Transport Tube and freeze. (Min: 1 mL)
Frozen.
If less than 1 mL of CSF is added to collection tube, pH of the supernatant will be too low for testing.
Ambient: Unacceptable; Refrigerated: 2 days; Frozen: 1 month
Reference Interval
0.060-0.190 mmol/L
Interpretive Data
Standard
Note
Hotline History
CPT Codes
84210
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0080312 | Pyruvic Acid, CSF | 14122-6 |
Aliases
- Pyruvate (Pyruvic Acid, CSF)
- Pyruvic Acid