Ordering Recommendation

Preferred initial screening test for pyruvate kinase deficiency.

Mnemonic

PK

Methodology

Quantitative Enzymatic

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or Pink (K2EDTA). Also acceptable: Green (Sodium or Lithium Heparin) or Yellow (ACD Solution A or B).

Specimen Preparation

Do not freeze. Transport 1 mL whole blood. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: Unacceptable; Refrigerated: 20 days; Frozen: Unacceptable

Reference Interval

4.6-11.2 U/g Hb

Interpretive Data



Compliance Category

Standard

Note

Patients who have recently received transfusions have normal donor cells that may mask PK deficient erythrocytes.

Hotline History

N/A

CPT Codes

84220

Components

Component Test Code* Component Chart Name LOINC
0080290 Pyruvate Kinase 32552-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • PK
  • Pyruvate Kinase (RBC)
Pyruvate Kinase