NMP22, Urine

0080281
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Example Reports
Abnormal
Normal

Ordering Recommendation

Aids in diagnosis of urothelial carcinoma in conjunction with standard diagnostic procedures and monitoring for tumor recurrence.

Mnemonic

NMP22

Methodology

Quantitative Enzyme Immunoassay

Performed

Thu

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

NMP22 testing should not be performed on patients who have had a total cystectomy or within 5 days of an invasive procedure, such as cystoscopy or catheterization of the urethra.

Collect

Single void of urine collected between midnight and noon. Urine Stabilization kit required (ARUP Supply #12594). Available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at (800) 522-2787.

Specimen Preparation

Follow instructions provided in the Urine Stabilization kit. Stabilized specimen should be blue/green in color.

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Urine not stabilized in NMP22 Urine Stabilizer Vial.

Remarks
Stability

Preserved: Ambient: 4 days; Refrigerated: 7 days; Frozen: 2 months

Reference Interval

0.0-10.0 U/mL

Interpretive Data

This test is intended as an aid in the management of patients with transitional cell carcinoma of the urinary tract (TCC/UT), and is used after surgical treatment to identify patients with residual or rapidly recurring TCC/UT. Values obtained with different test methods should not be used interchangeably. ARUP uses the Alere NMP22 Test Kit, an enzyme immunoassay (EIA) method. Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86316

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Components

Component Test Code* Component Chart Name LOINC
0080281 NMP22, Urine 31134-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Bladder Tumor Associated Antigen
  • NMP22
  • Nuclear Matrix Protein
NMP22, Urine