Ordering Recommendation

Preferred initial screening test for G6PD deficiency. For genetic testing, refer to Glucose-6-Phosphate Dehydrogenase (G6PD) 2 Mutations (0051684) for individuals of African descent or Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) Sequencing (2007163) for individuals with other high-risk ethnic backgrounds.

Mnemonic
G6PD
Methodology

Quantitative Enzymatic

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Yellow (ACD Solution A). Also acceptable: Green (Sodium or Lithium Heparin), Lavender (K2EDTA or K3EDTA), or Pink (K2EDTA). Enzyme most stable in acid citrate dextrose (ACD).

Specimen Preparation

Do not freeze. Transport 3 mL whole blood. (Min: 1.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

Effective November 17, 2014
9.9-16.6 U/g Hb

Interpretive Data



Compliance Category

FDA

Note

Patients who have recently received transfusions have normal donor cells that may mask G-6-PD deficient erythrocytes.

Hotline History
N/A
CPT Codes

82955

Components
Component Test Code* Component Chart Name LOINC
0080135 Glucose-6-Phosphate Dehydrogenase 32546-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • G-6-PD
  • G6PD Erythrocytes
  • RBC G6PD test
Glucose-6-Phosphate Dehydrogenase