Ordering Recommendation

Screen and diagnose hyperaldosteronism.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

24-hour urine. Urine must be refrigerated during collection.

Specimen Preparation

Add 1 g boric acid per 100 mL urine. Transfer 4 mL aliquot of urine from a 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume and collection time interval on transport tube and test request form. Also acceptable: Preserved urine if the pH of the specimen is adjusted to 2-4 with 6M HCl or 50 percent acetic acid or unpreserved urine if frozen immediately after collection.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated, if preserved with HCl or acetic acid.

Unacceptable Conditions

Ambient: 4 hours; Refrigerated: (with preservative): 5 days; Frozen: 1 month


Quantitative Chemiluminescent Immunoassay (CLIA)


Tue, Thu, Sat


2-5 days

Reference Interval

Effective October 6, 2014

Test Number
Reference Interval
  Aldosterone, Urine 1.2-28.1 µg/d
  Creatinine, Urine - per 24h
Male (mg/d)
Female (mg/d)
3-8 years 140-700 140-700
9-12 years 300-1300 300-1300
13-17 years 500-2300 400-1600
18-50 years 1000-2500 700-1600
51-80 years 800-2100 500-1400
81 years and older 600-2000 400-1300

Interpretive Data

Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume.  For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.

Compliance Category



Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0020207 Creatinine, Urine - per volume 2161-8
0020208 Creatinine, Urine - per 24h 2162-6
0097110 Total Volume 19153-6
0097111 Hours Collected 30211-7
0099020 Aldosterone, Urine 1765-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • 24 hr aldosterone
  • urine aldosterone
Aldosterone, Urine