C-Telopeptide, Beta-Cross-Linked, Serum

0070416
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Additional Technical Information

Ordering Recommendation

Preferred test to measure bone resorption and monitor response to antiresorptive therapy (eg, bisphosphonates, hormone replacement therapy) in postmenopausal women and individuals with osteoporosis.

Mnemonic

CTX

Methodology

Quantitative Electrochemiluminescent Immunoassay

Performed

Tue, Thu, Sat

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

For patients receiving therapy with high biotin doses (e.g. greater than 5 mg/day), specimen should not be drawn until at least 8 hours after the last biotin administration.

Collect

Serum separator tube, pink (K2EDTA), or green (lithium heparin).

Specimen Preparation

Allow serum separator tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 4 hours; Refrigerated: 8 hours; Frozen: 3 months

Reference Interval

Effective November 14, 2011

Age
 Female
 Male
6 months-6 years 500-1800 pg/mL 500-1700 pg/mL
7-9 years 566-1690 pg/mL 522-1682 pg/mL
10-12 years 503-2077 pg/mL 553-2071 pg/mL
13-15 years 160-1590 pg/mL 485-2468  pg/mL
16-17 years 167-933 pg/mL 276-1546 pg/mL
18-29 years 64-640 pg/mL 87-1200 pg/mL
30-39 years 60-650 pg/mL 70-780 pg/mL
40-49 years 40-465 pg/mL 60-700 pg/mL
50-69 years 40-840 pg/mL
70 years or greater 52-847 pg/mL
Postmenopausal 104-1008 pg/mL

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

82523

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Components

Component Test Code* Component Chart Name LOINC
0070415 C-Telopeptide, Beta-Cross-Linked, Serum 41171-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Beta-CTx
  • B-Cross Laps
  • B-CTx
  • Beta-Cross Laps
  • bone resorption marker
  • C-Telopeptide
  • C-terminal collagen crosslinks
  • Carboxy terminal collagen crosslinks
  • Collagen C Telopeptide
  • Collagen Type I-C
  • Collagen Type I-C Telopeptide
  • CTx
C-Telopeptide, Beta-Cross-Linked, Serum