Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube or plasma separator tube. Also acceptable: green (lithium heparin).

Specimen Preparation

Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature


Unacceptable Conditions

Contaminated, severely hemolyzed, icteric, or lipemic specimens.


After separation from cells: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)


Quantitative Immunoturbidimetry




Within 24 hours

Reference Interval

Male - 18 years & older: 2.2-5.0 mg/L
Female - 18 years & older: 1.9-4.4 mg/L

Interpretive Data

People of African descent and those residing at 5,200 feet (1,600 meters) above sea level were found to have a 6% higher normal value.  These differences were additive.  Reference intervals have not been established for pregnant females, patients under 18 years of age, and recent or frequent blood donors.

Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states.  In general, to increase sensitivity and specificity, the measurement of serum soluble transferrin receptor should be performed in combination with other tests of iron status, including ferritin, TIBC, and serum iron (refer to table below).

Tests for Changes in:
Iron Deficiency Anemia
Anemia of Chronic Disease
Iron Deficiency & Anemia of Chronic Disease
Ferritin Iron Stores Low High Normal or High
TIBC Iron Status High Low Normal or High
Serum Iron Iron Status Low Low Low
sTfR Iron Status High Normal High

Compliance Category



Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0070283 Soluble Transferrin Receptor 30248-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • sTfR
  • TfR
  • Transferrin Receptor
  • Transferrin Receptor Level
Soluble Transferrin Receptor