Ordering Recommendation

Aids in the detection of vitamin B12 or folate deficiency in individuals with macrocytic or unexplained anemia, or unexplained neurologic disease.

Mnemonic
B12/FOL
Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube. Also acceptable: Green (sodium or lithium heparin).

Specimen Preparation

Protect from light during collection, storage, and shipment. Allow serum to clot completely at room temperature before centrifuging. Transfer 2 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

EDTA plasma. Hemolyzed or refrigerated specimens exposed to light for more than 24 cumulative hours.

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: 8 hours; Frozen: 3 months

Reference Interval
Test Number
Components
Reference Interval
0070150 Vitamin B12 Effective December 2, 2013
180-914 pg/mL
0070070 Folate, Serum Less than or equal to 3.9 ng/mL: Deficient
4.0-5.8 ng/mL: Indeterminate
Greater than or equal to 5.9 ng/mL: Normal                

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

82607; 82746

Components
Component Test Code* Component Chart Name LOINC
0070070 Folate, Serum 2284-8
0070150 Vitamin B12 2132-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • B12 & Folate
  • B12/Folate, Serum
  • Folate & Vitamin B12
  • Folate and Vitamin B12
  • Folic Acid
  • Vitamin B9
Vitamin B12 and Folate