Vitamin B12

0070150
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Ordering Recommendation

Aids in the detection of vitamin B12 deficiency in individuals with macrocytic or unexplained anemia, or unexplained neurologic disease.

Mnemonic

B12

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube. Also acceptable: Green (sodium or lithium heparin).

Specimen Preparation

Protect from light during collection, storage, and shipment. Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

EDTA plasma. Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 24 hours; Frozen: 3 months

Reference Interval

Effective December 2, 2013
180-914 pg/mL

Interpretive Data



Compliance Category

FDA

Note

Also refer to Methylmalonic Acid (MMA), Serum Quantitative (0099431).  Some references suggest that elevated methylmalonic acid is an early and sensitive indicator of vitamin B12 (cobalamin) deficiency.

Hotline History

N/A

CPT Codes

82607

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Components

Component Test Code* Component Chart Name LOINC
0070150 Vitamin B12 2132-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • B12 Assay
  • B12 Vitamin
  • B12, Serum
  • CblC
  • Cobalamin
  • Methylcobalamin
  • Vit B12
Vitamin B12