Vitamin B12
Ordering Recommendation
Aids in the detection of vitamin B12 deficiency in individuals with macrocytic or unexplained anemia, or unexplained neurologic disease.
New York DOH Approval Status
Specimen Required
Serum separator tube. Also acceptable: Green (sodium or lithium heparin).
Protect from light during collection, storage, and shipment. Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.5 mL)
Frozen.
EDTA plasma. Hemolyzed specimens.
After separation from cells: Ambient: 8 hours; Refrigerated: 24 hours; Frozen: 3 months
Methodology
Quantitative Chemiluminescent Immunoassay (CLIA)
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Effective December 2, 2013
180-914 pg/mL
Interpretive Data
FDA
Note
Also refer to Methylmalonic Acid (MMA), Serum Quantitative (0099431). Some references suggest that elevated methylmalonic acid is an early and sensitive indicator of vitamin B12 (cobalamin) deficiency.
Hotline History
CPT Codes
82607
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0070150 | Vitamin B12 | 2132-9 |
Aliases
- B12 Assay
- B12 Vitamin
- B12, Serum
- CblC
- Cobalamin
- Methylcobalamin
- Vit B12