Testosterone, Bioavailable and Sex Hormone Binding Globulin (Includes Total Testosterone), Adult Male

0070102
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Abnormal
Normal
Ordering Recommendation

Acceptable test for the evaluation of suspected hypogonadism in men. Not recommended for use in women and children.

Mnemonic
BIO T
Methodology

Quantitative Electrochemiluminescent Immunoassay
The concentrations of free and bioavailable testosterone are derived from mathematical expressions based on constants for the binding of testosterone to albumin and/or sex hormone binding globulin.

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Collect specimen between 6-10 a.m.

Collect

Serum separator tube or green (lithium heparin).

Specimen Preparation

Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

EDTA plasma.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 2 months

Reference Interval
Test Number
 Components
 Reference Interval
0070111 Testosterone Free, Adult Male Male:
14-15 years:  3-138 pg/mL
16-17 years:  38-173 pg/mL
18 years and older: 47-244 pg/mL

Tanner Stage IV:  35-169 pg/mL
Tanner Stage V:  41-239 pg/mL
0070130 Testosterone, Adult Male Male:
14-15 years: 33-585 ng/dL
16-17 years: 185-886 ng/dL
18-39 years: 300-1080 ng/dL
40-59 years: 300-890 ng/dL
60 years and older: 300-720 ng/dL

Tanner Stage IV: 165-854 ng/dL
Tanner Stage V: 194-783 ng/dL
0099375 Sex Hormone Binding Globulin
Age Male Female
1-30 days
31-364 days
1-3 years
4-6 years
7-9 years
10-12 years
13-15 years
16-17 years
18 years and older		 13-85 nmol/L
70-250 nmol/L
50-180 nmol/L
45-175 nmol/L
28-190 nmol/L
23-160 nmol/L
13-140 nmol/L
10-60 nmol/L
11-80 nmol/L		 14-60 nmol/L
60-215 nmol/L
60-190 nmol/L
55-170 nmol/L
35-170 nmol/L
17-155 nmol/L
11-120 nmol/L
19-145 nmol/L
30-135 nmol/L
Tanner Stage I
Tanner Stage II
Tanner Stage III
Tanner Stage IV
Tanner Stage V		 26-186 nmol/L
22-169 nmol/L
13-104 nmol/L
11-60 nmol/L
11-71 nmol/L		 30-173 nmol/L
16-127 nmol/L
12-98 nmol/L
14-151 nmol/L
23-165 nmol/L

Component
 Reference Interval
Testosterone, Bioavailable, Adult Male 14-15 years:  10-337 ng/dL
16-17 years: 35-509 ng/dL
18 years and older: 131-682 ng/dL

Tanner Stage IV:  40-485 ng/dL
Tanner Stage V:  124-596 ng/dL
Testosterone, Percentage Free, Adult Male 1.6-2.9%

Interpretive Data

The concentrations of free and bioavailable testosterone are derived from mathematical expressions based on constants for the binding of testosterone to albumin and/or sex hormone binding globulin.

Compliance Category

FDA

Note

Bioavailable testosterone includes free plus weakly bound (non-SHBG bound) testosterone.  Bioavailable testosterone is an assessment of the biologically active testosterone in serum.

Please refer to individual components for stability of sample for this test.  This test is not recommended for females or children.  For testing on females or children refer to Testosterone, Bioavailable & Sex Hormone Binding Globulin (Includes Total Testosterone), Females or Children (0081057).

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/12/2019
X
N/A
CPT Codes

84402; 84403; 84270

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Components
Component Test Code* Component Chart Name LOINC
0070113 Testosterone, Free Calculation 2991-8
0070114 Testosterone, Percentage Free 15432-8
0070130 Testosterone, Adult Male 2986-8
0070134 Testosterone, Bioavailable 2990-0
0099375 Sex Hormone Binding Globulin 13967-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • TeBG
  • Testosterone-estrogen Binding Globulin
Testosterone, Bioavailable and Sex Hormone Binding Globulin (Includes Total Testosterone), Adult Male