Ordering Recommendation
Mnemonic
GH 60
Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plasma separator tube or serum separator tube. Collect one tube per timed specimen. Also acceptable: Green (sodium or lithium heparin) or lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature.  Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma per timed specimen to individual ARUP Standard Transport Tubes. (Min: 0.4 mL per timed specimen)

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated

Unacceptable Conditions

Tissue or urine. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months

Reference Interval
Interpretive Data

Growth hormone stimulation tests should induce a peak of greater than 5 ng/mL in children and greater than 4 ng/mL in adults; lower values suggest growth hormone deficiency. For children, some experts consider values of 5-8 ng/mL equivocal and only peak values of greater than 8 ng/mL as truly normal.

For suppression testing, normal subjects have growth hormone concentrations of less than 0.8 ng/mL within 2 hours of ingestion of a 75 or 100 gram glucose dose. Patients with acromegaly fail to show normal suppression.  

No compliance statements are in use for this test.

Note

This Growth Hormone assay is now standardized to the Recombinant Second International Standard (IS): 98/574. Growth hormone results read approximately 25 percent lower than with the previous standards (First IS: 80/505). Reference ranges have also been modified according to the assay manufacturer.

Hotline History
N/A
CPT Codes

83003

Components
Component Test Code* Component Chart Name LOINC
0070083 Growth Hormone 60 Minutes 14146-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • GH
  • GH testing
  • GHRH
  • Growth Hormone Provocative Test
  • Growth Hormone Stimulation
  • growth hormone, Serum
  • hGH
  • Human Growth Hormone
  • Somatotrophic Hormone
  • Somatotropin
Growth Hormone, 60 Minutes