Ordering Recommendation

Not a first-line test in the evaluation of growth disorders. Aids in workup of suspected anterior hypopituitarism.

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube. Also acceptable: Green (sodium heparin).

Specimen Preparation

Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Tissue or urine. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Reference Interval

Test Number
Components
Reference Interval
  IGF Binding Protein 3
Age
Male (ng/mL)
Female (ng/mL)
0-12 months 1039-3169 1039-3169
1-3 years 972-4123 1590-4225
4-5 years 1843-4968 2169-4790
6-7 years 1838-4968 2188-4996
8-9 years 1932-5858 2072-5504
10-11 years 1828-6592 2456-6992
12-13 years 2134-6598 2838-6846
14-15 years 2330-6550 2654-6680
16-17 years 2380-6400 2756-6908
18-19 years 2340-6632 2700-6492
20-24 years 2404-5948 3032-5992
25-29 years 2614-5792 2926-5858
30-34 years 2500-5806 2878-6650
35-39 years 2474-5208 2786-6084
40-44 years 2360-5560 2514-6014
45-49 years 2314-5700 2838-4954
50-54 years 2528-5050 2562-5596
55-59 years 2482-5460 2574-5914
60-64 years 2592-4770 2684-5130
65 years and older 2698-5680 2462-5274
Tanner Stage I 1878-6190 2314-6086
Tanner Stage II 2112-6208 2732-6738
Tanner Stage III 2372-6602 2870-7068
Tanner Stage IV & V 2336-6414 2756-7232

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

82397

Components

Component Test Code* Component Chart Name LOINC
0070060 IGF Binding Protein 3 2483-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • IGF Binding Protein-3
  • IGFBP-3
  • IGFBP3
  • Insulin-Like Growth Factor Binding Protein-3
  • Somatomedin C binding protein
Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3)