0070060
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  Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3)

IGFBP-3
Example Reports
Abnormal
Normal

Ordering Recommendation

Not a first-line test in the evaluation of growth disorders. Aids in workup of suspected anterior hypopituitarism.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube. Also acceptable: Green (sodium heparin).

Specimen Preparation

Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Tissue or urine. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Methodology

Quantitative Chemiluminescent Immunoassay (CLIA)

Performed

Sun-Sat

Reported

1-2 days

Reference Interval

Test Number
 Components
 Reference Interval
  IGF Binding Protein 3
Age
 Reference Intervals (ng/mL)
0-7 days 500-900
8-14 days 500-1400
15 days-11 months Reference intervals not available
1 year 700-3600
2 years 800-3900
3 years 900-4300
4 years 1000-4700
5 years 1100-5200
6 years 1300-5600
7 years 1400-6100
8 years 1600-6500
9 years 1800-7100
10 years 2100-7700
11 years 2400-8400
12 years 2700-8900
13 years 3100-9500
14 years 3300-10000
15 years 3500-10000
16 years 3400-9500
17 years 3200-8700
18 years 3100-7900
19 years 2900-7300
20 years 2900-7200
21-25 years 3400-7800
26-30 years 3500-7600
31-35 years 3500-7000
36-40 years 3400-6700
41-45 years 3300-6600
46-50 years 3300-6700
51-55 years 3400-6800
56-60 years 3400-6900
61-65 years 3200-6600
66-70 years 3000-6200
71-75 years 2800-5700
76-80 years 2500-5100

Age
 Reference Intervals (ng/mL)
81-85 years 2200-4500
86 years and older Reference intervals not established

Interpretive Data




Tanner Stage Male (ng/mL) Female (ng/mL)
Tanner Stage I 1400-5200 1200-6400
Tanner Stage II 2300-6300 2800-6900
Tanner Stage III 3100-8900 3900-9400
Tanner Stage IV 3700-8700 3300-8100
Tanner Stage V 2600-8600 2700-9100

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
10/20/2025
X
X
N/A

CPT Codes

82397

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Components

Component Test Code* Component Chart Name LOINC
0070060 IGF Binding Protein 3 2483-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • IGF Binding Protein-3
  • IGFBP-3
  • IGFBP3
  • Insulin-Like Growth Factor Binding Protein-3
  • Somatomedin C
Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3)