Ordering Recommendation

Screening test for fetal aneuploidy in conjunction with other biomarkers and ultrasonography. Indicator of fetal well-being and placental function.

Mnemonic

EST

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma.

Remarks

Patient gestational age required.

Stability

After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective November 19, 2012

Based on gestational age:
25 weeks 1.9 - 6.7 ng/mL
26 weeks 2.0 - 7.3 ng/mL
27 - 29 weeks 2.1 - 9.1 ng/mL
30 - 31 weeks 2.4 - 10.6 ng/mL
32 - 37 weeks 2.6 - 16.7 ng/mL
Nonpregnant Female Less than 0.08 ng/mL
Male Less than 0.16 ng/mL

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

82677

Components

Component Test Code* Component Chart Name LOINC
0070052 Estriol, Serum 2251-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • E3
  • Estriol
  • UE3
  • Unconjugated Estriol
Estriol, Serum