Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis. May assist when diagnosing and monitoring mast-cell activation disorders or when evaluating histamine production over a longer time frame.
Quantitative Enzyme Immunoassay
Random or 24-hour urine in a plastic container. Refrigerate during collection.
Transfer a 4 mL aliquot from a well-mixed random or 24-hour collection to an ARUP Standard Transport Tube and freeze immediately. (Min: 1 mL) Record total volume and collection time interval on transport tube and test request form.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Ambient: Unacceptable; Refrigerated: 6 hours; Frozen: 6 months
Effective February 21, 2012
|Histamine, Urine - ratio to CRT||0-450 nmol/g crt|
|Histamine, Urine, Excretion - 24h||0-60 µg/day|
Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
If 24-hour urine is submitted, the excretion will be calculated. If random urine is submitted, the result will be reported as "Not applicable."
|Component Test Code*||Component Chart Name||LOINC|
|0020207||Creatinine, Urine - per volume||2161-8|
|0070039||Histamine, Urine - per volume||33290-8|
|0070041||Histamine, Urine - ratio to CRT||25925-9|
|2005776||Histamine, Urine, Excretion - 24 h||9410-2|
- urine histamine