Ordering Recommendation

Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis; may assist in diagnosing and monitoring of mast-cell activation disorders.




Quantitative Enzyme-Linked Immunosorbent Assay


Tue, Sat


1-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Lavender (EDTA) or pink (K2EDTA). Collect in a pre-chilled tube and on ice.

Specimen Preparation

Centrifuge refrigerated and separate upper two-thirds of plasma within 20 minutes. If EDTA gel collection tube is used, the plasma must be collected immediately after centrifugation and frozen separately. Transfer 1 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Lipemic or hemolyzed specimens.


After separation from cells: Ambient: Unacceptable; Refrigerated: 6 hours; Frozen: 6 months

Reference Interval

Effective June 13, 2011

0-8 nmol/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0070036 Histamine, Plasma 34316-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • plasma histamine
Histamine, Plasma