Ordering Recommendation

Screen, diagnose, and monitor diseases associated with excess or deficient cortisol production.

Mnemonic

CORTISOL30

Methodology

Quantitative Electrochemiluminescence Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Collect 1 timed specimen at 30 minutes.

Collect

Serum separator tube (SST) or Plain Red, green (lithium heparin), Lavender (K2 EDTA and K3 EDTA), or pink (K2 EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL) Specimen must be labeled with time drawn.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 4 days; Frozen: 12 months (avoid repeated freeze/thaw cycles)

Reference Interval

By report

Interpretive Data

Normal peak serum cortisol is greater than 18.0 µg/dL at 30 or 60 minutes after 250 micrograms of cosyntropin IV.

Compliance Category

FDA

Note

To convert to nmol/L, multiply µg/dL by 27.6.

Hotline History

N/A

CPT Codes

82533

Components

Component Test Code* Component Chart Name LOINC
0070032 Cortisol 30 Min 26530-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Adrenal Corticotropin Hormone
  • Corticotropin
  • Cortisol
  • Cortrosyn
  • Cosyntropin
Adrenocorticotropic Hormone Stimulation, 30 Minutes