Ordering Recommendation

Aids in the diagnosis of adrenal insufficiency and determining the presence of anterior pituitary tumors.

Mnemonic
ACTH
Methodology

Quantitative Electrochemiluminescent Immunoassay (ECLIA)

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Morning collection (7 a.m. to 10 a.m.) is preferred.

Collect

Lavender (K2EDTA) or Pink (K2EDTA). Collection tube must be siliconized glass or plastic.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, heparinized plasma, tissue or urine. Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 3 hours; Refrigerated: 4 hours; Frozen: 1 month (No freeze/thaw cycles.)

Reference Interval

Effective August 5, 2019
7.2 - 63.3 pg/mL (a.m. draws)

Interpretive Data

Reference interval based on samples collected between 7 a.m. and 10 a.m. No reference intervals established for p.m. collections. Pediatric reference values are the same as adults (Acta Paediatr Scand 1981;70:341-345). This assay measures intact ACTH 1-39; some types of synthetic ACTH and ACTH fragments are not detected by this assay.

No compliance statements are in use for this test.

Note

No reference intervals established for p.m. collections.

Hotline History
N/A
CPT Codes

82024

Components
Component Test Code* Component Chart Name LOINC
0070010 Adrenocorticotropic Hormone 2141-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ACTH
  • Adrenal Corticotropin Hormone
  • Corticotropin
  • Cortrosyn
  • Cosyntropin
Adrenocorticotropic Hormone