Ordering Recommendation

Diagnose and monitor medullary thyroid carcinoma (MTC). Secondary test to assist in diagnosing multiple endocrine neoplasia type II and familial MTC.

Mnemonic
CALCI
Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Tissue or urine. EDTA plasma. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months

Reference Interval

Male 3 years and older: 0.0-7.5 pg/mL
Female 3 years and older: 0.0-5.1 pg/mL

Interpretive Data

Calcitonin levels greater than 100 pg/mL may occur in the following conditions: medullary thyroid carcinomas (MTC), leukemias, and myeloproliferative disorders.

Provocative testing (calcium) is suggested in patients with MTC if the calcitonin is not clearly diagnostic.

The Siemens Immulite® 2000 method is used.  Results obtained with different assay methods or kits cannot be used interchangeably.  Calcitonin is useful in monitoring medullary thyroid carcinoma.  The calcitonin assay value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

82308

Components
Component Test Code* Component Chart Name LOINC
0070006 Calcitonin 1992-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Human Calcitonin
  • Thyrocalcitonin
Calcitonin