Not recommended as a stand-alone test. Parvovirus B19 Antibodies, IgG and IgM (0065120) is preferred.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Contaminated, heat-inactivated, hemolyzed, lipemic, or icteric specimens.
Mark specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
0.90 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody.
0.91-1.09 IV: Equivocal - Repeat testing in 7-21 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.
|Component Test Code*||Component Chart Name||LOINC|
|0065122||Parvovirus B19 Antibody IgM||5274-6|
- B19 IgM Antibodies
- Erythrovirus B19 IgM
- Human Parvovirus B19 IgM