Parvovirus B 19 Antibody, IgM

0065122
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Negative
Positive

Ordering Recommendation

Not recommended as a stand-alone test. Parvovirus B19 Antibodies, IgG and IgM (0065120) is preferred.

Mnemonic

PARVO M

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks

Mark specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

0.90 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody.
0.91-1.09 IV: Equivocal - Repeat testing in 7-21 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86747

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Components

Component Test Code* Component Chart Name LOINC
0065122 Parvovirus B19 Antibody IgM 5274-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • B19
  • B19 IgM Antibodies
  • Erythrovirus B19 IgM
  • Human Parvovirus B19 IgM
Parvovirus B 19 Antibody, IgM