Not recommended as a stand-alone test. Parvovirus B19 Antibodies, IgG and IgM (0065120) is preferred.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Contaminated, heat-inactivated, hemolyzed, lipemic, or icteric specimens.
Mark specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
0.90 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody.
0.91-1.09 IV: Equivocal - Repeat testing in 7-21 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.
No compliance statements are in use for this test.
|Component Test Code*||Component Chart Name||LOINC|
|0065122||Parvovirus B19 Antibody IgM||5274-6|
- B19 IgM Antibodies
- Erythrovirus B19 IgM
- Human Parvovirus B19 IgM