Differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). Differentiate early IgM response to infection from persistent low-level titer. Because of cross-reactivity, a C. pneumoniae-specific reaction will exhibit titers two-fold or greater than C. trachomatis or C. psittaci serology. Limited value in the diagnosis of most oculogenital (eg, eyes, genitalia) chlamydial infections.
Semi-Quantitative Indirect Fluorescent Antibody
Plain red or serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."
Contaminated, hemolyzed, or hyperlipemic sera.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
< 1:64 C. pneumoniae IgG.
< 1:64 C. psittaci IgG.
< 1:64 C. trachomatis IgG.
< 1:20 C. pneumoniae IgM.
< 1:20 C. psittaci IgM.
< 1:20 C. trachomatis IgM.
Refer to individual components.
Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
86631 x3; 86632 x3
|Component Test Code*||Component Chart Name||LOINC|
|0065101||C. pneumoniae IgM Titer||6914-6|
|0065102||C. trachomatis IgM Titer||6920-3|
|0065103||C. psittaci IgM Titer||6917-9|
|0065104||C. pneumoniae IgG Titer||6913-8|
|0065106||C. trachomatis IgG Titer||6919-5|
|0065107||C. psittaci IgG Titer||6916-1|
- Chlamydia IgG, IgM Ab
- CT IgG, IgM Ab