Ordering Recommendation

Differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). Differentiate early IgM response to infection from persistent low-level titer. Because of cross-reactivity, a C. pneumoniae-specific reaction will exhibit titers two-fold or greater than C. trachomatis or C. psittaci serology. Limited value in the diagnosis of most oculogenital (eg, eyes, genitalia) chlamydial infections.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Plain red or serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.4 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature


Unacceptable Conditions

Contaminated, hemolyzed, or hyperlipemic sera.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)


Semi-Quantitative Indirect Fluorescent Antibody (IFA)




1-4 days

Reference Interval

< 1:64 C. pneumoniae IgG.     
< 1:64 C. psittaci IgG.
< 1:64 C. trachomatis IgG.
< 1:20 C. pneumoniae IgM.     
< 1:20 C. psittaci IgM.
< 1:20 C. trachomatis IgM.

Interpretive Data

Refer to individual components.

Compliance Category

Analyte Specific Reagent (ASR)


Hotline History


CPT Codes

86631 x3; 86632 x3


Component Test Code* Component Chart Name LOINC
0065101 C. pneumoniae IgM Titer 6914-6
0065102 C. trachomatis IgM Titer 6920-3
0065103 C. psittaci IgM Titer 6917-9
0065104 C. pneumoniae IgG Titer 6913-8
0065106 C. trachomatis IgG Titer 6919-5
0065107 C. psittaci IgG Titer 6916-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Chlamydia IgG, IgM Ab
  • CT IgG, IgM Ab
Chlamydia Antibody Panel, IgG & IgM by IFA