Use to detect herpes simplex virus (HSV) by viral culture and differentiate types 1 and 2. Molecular testing is generally preferred; refer to Herpes Simplex Virus (HSV-1/HSV-2) Subtype by PCR (2010095). Orthopoxviruses, including monkeypox virus, cannot be identified clinically using this testing method. Refer to https://www.aruplab.com/monkeypox-testing for more information.
Cell Culture/Microscopy/Immunofluorescent Stain
New York DOH Approval Status
Buccal mucosa, eye, genital, rectal, throat or vesicle swab, neonatal surface swab, or bronchoalveolar lavage, tissue, or vesicle fluid.
Fluid: Transfer 3 mL specimen to a sterile container. (Min: 0.5 mL) Also acceptable: Transfer to 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Swab or Tissue: Place in 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
ARUP will NOT perform viral culture for patients suspected or confirmed to have monkeypox infection. Blood, CSF, plasma, or serum. Bacterial transport systems; molecular transport systems; calcium alginate, dry, or wood swabs.
Specimen source preferred.
Ambient: 2 hours; Refrigerated: 72 hours; Frozen: Unacceptable
Culture negative for herpes simplex virus.
If culture is positive for HSV, then HSV typing test will be added. Additional charges apply.
Herpes Simplex Virus by PCR (ARUP test code 0060041) on CSF specimens is standard of care for diagnosing HSV meningitis/meningoencephalitis.
87255; if reflexed, add 87140 x2
|Component Test Code*||Component Chart Name||LOINC|
|0065065||Culture, HSV with Reflex to Typing||5859-4|
- Herpes Culture
- Herpes Simplex Viral Culture
- HSV type 1
- HSV type 2
- HSV-1 or HSV-2
- HSV1 and HSV2