Ordering Recommendation

Monitor levels of antimicrobial drug, nafcillin.

Mnemonic
ML NAF
Methodology

Quantitative Bioassay

Performed

Sun-Sat

Reported

2-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red.

Specimen Preparation

Aseptically remove 2 mL serum to a sterile tube (ARUP supply #43115) and freeze. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL).

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Plasma.

Remarks

Required information includes: time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.

Stability

Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week

Reference Interval
Interpretive Data

Normal peak serum concentration for nafcillin is 7.7 µg/mL with a 1 g PO dose, 7.6 µg/mL with a 1 g IM dose or 40 µg/mL with a 500 mg IV dose. Trough serum concentration is not well established.

For bioassay measurements, the presence of other antimicrobial agents may interfere with the assay. Other factors that may influence antimicrobial levels include inherent differences among patients and their underlying physical conditions as well as the dose and route of administration of the antimicrobial agent.

Compliance Category

Standard

Note

Please include time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours. This information is important for laboratory handling and essential for subsequent physician interpretation of results 

Hotline History
N/A
CPT Codes

80299

Components
Component Test Code* Component Chart Name LOINC
0060854 Antibiotic Level, Nafcillin 10993-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Nafcillin Level
  • Nafcillin Level, BA
  • Nafcillin serum level
Antibiotic Level, Nafcillin