Connect Sign In
Antibiotic Level, Piperacillin
Ordering Recommendation
Monitor levels of antimicrobial drug, piperacillin.
New York DOH Approval Status
Specimen Required
Plain red.
Aseptically remove 2 mL serum to a sterile tube (ARUP supply #43115) and freeze. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
Frozen.
Plasma.
Required information includes: time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.
Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week
Methodology
Quantitative Bioassay
Performed
Sun-Sat
Reported
2-3 days
Reference Interval
Interpretive Data
Normal peak serum concentration for piperacillin is 389-484 µg/mL with a 4 g IV dose of piperacillin, 209 µg/mL with a 3.375 g IV dose of piperacillin/tazobactam, or 224 µg/mL with a 4.5 g IV dose of piperacillin/tazobactam. Trough serum concentration is not well established.
For bioassay measurements, the presence of other antimicrobial agents may interfere with the assay. Other factors that may influence antimicrobial levels include inherent differences among patients and their underlying physical conditions as well as the dose and route of administration of the antimicrobial agent.
Standard
Note
Please include time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours. This information is important for laboratory handling and essential for subsequent physician interpretation of results.
Hotline History
CPT Codes
80299
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0060853 | Antibiotic Level, Piperacillin | 3972-7 |
Aliases
- piperacillin-tazobactam
- Zosyn
- Pipercillin serum level
