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Antimicrobial Susceptibility, AFB/Mycobacterium tuberculosis Primary Panel
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Ordering Recommendation
Mnemonic
Methodology
Broth Macrodilution
Performed
Sun-Sat
Reported
21-28 days
New York DOH Approval Status
Specimen Required
Actively growing isolate of Mycobacterium tuberculosis in pure culture.
Transport sealed container with pure culture on solid or liquid media. Place each specimen in an individually sealed bag.
Room temperature.
Submit specimen according to Infectious Substance, Category A, shipping guidelines.
Mixed cultures or non-viable organisms. Organisms submitted on agar plate.
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
The interpretation provided is based on results for the following drugs at the stated concentrations:
Drugs tested: Ethambutol: 5.0 µg/mL, isoniazid: 0.1 µg/mL (0.4 µg/mL if resistant to 0.1 µg/mL), pyrazinamide: 100 µg/mL, and rifampin: 1.0 µg/mL.
This procedure screens isolates of M. tuberculosis complex for drug resistance. The procedure does not use serial dilutions to provide quantitative MIC values. Single critical concentrations for each antimycobacterial agent used have been defined by the United States Public Health Service.
FDA
Note
M. tuberculosis complex isolates mono-resistant to Pyrazinamide (PZA) will be further identified to species by PCR. Additional charges apply.
Hotline History
CPT Codes
87188 x4. CPT codes vary based on method.
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0060347 | Susceptibility, M. tuberculosis Primary | 29576-6 |
Aliases
- AFB primary panel
- Ethambutol susceptibility
- isoniazid susceptibility
- pyrazinamide susceptibility
- rifampin susceptibility
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