Clostridium difficile Culture with Reflex to Cytotoxin Cell Assay
Reference method for diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea (turnaround time ≥96 hours). Preferred initial test is Clostridium difficile toxin B gene (tcdB) by PCR (2002838).
Negative culture reported at 4 days. Positive culture reported as soon as detected.
New York DOH Approval Status
Stool or Tissue
Stool: Transfer 5 mL stool to an unpreserved stool transport vial (ARUP supply #40910) OR place 5 mL stool in enteric transport media (Cary-Blair) (ARUP supply #29799). (Min: 1 mL) Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Tissue: Transfer specimen immediately into anaerobe transport media (ARUP supply #16426), available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Stool: Frozen. Tissue: Room Temperature.
Multiple specimens (more than one in 24 hours), formed stools, or stool in PVA or formalin.
Unpreserved or preserved Stool: Ambient: 2 hours; Refrigerated: 48 hours; Frozen: 1 week. Tissue: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable.
Culture negative for Clostridium difficile.
For routine stool screening, refer to Clostridium difficile toxin B gene (tcdB) by PCR (ARUP test code 2002838).
If Clostridium difficile culture is positive, then Clostridium difficile Cytotoxin Cell Assay will be added. Additional charges apply.
87075; if positive add 87076; if reflexed add 87230
|Component Test Code*||Component Chart Name||LOINC|
|0060140||Culture, Clostridium difficile||562-9|
- C. diff culture
- C. difficile Culture
- Clostridioides difficile
- Culture, Clostridium difficile