Ordering Recommendation

Aid in the diagnosis of invasive/disseminated aspergillosis.

Mnemonic
ASPERAG
Methodology

Semi-quantitative Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red or serum separator tube.

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transfer 2 mL serum to a sterile ARUP Standard Transport Tube (ARUP Supply #43115). Available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Plasma. Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week

Reference Interval
Test Number
Components
Reference Interval
  Aspergillus Galactomannan Antigen, Serum Negative
  Aspergillus Galactomannan Index By report

Interpretive Data

Negative results do not exclude the diagnosis of invasive aspergillosis. A single positive test result (index equal to or greater than 0.5) should be clinically correlated by testing a separate serum specimen because many agents (e.g. foods, antibiotics) may cross-react with the test. If invasive aspergillosis is suspected in high-risk patients, serial sampling is recommended.

The false-positive rate is higher in children than in adults. (Cancer 91:311, 2001; J.Clin Oncol 20:1898,2002; Mycosis 41:373,1998).

Compliance Category

FDA

Note

For bronchial specimens refer to Aspergillus Galactomannan Antigen by EIA, Bronchoscopy (ARUP test code 2003150). For sputum or tissue specimens, refer to Aspergillus Species by PCR (ARUP test code 3000265).

Hotline History
N/A
CPT Codes

87305

Components
Component Test Code* Component Chart Name LOINC
0060272 Aspergillus Galactomannan Antigen, Serum 44099-0
0060273 Aspergillus Galactomannan Index 62467-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Aspergillosis
  • Aspergillus species
  • Galacto
  • Galactomannan
  • Galactomannan polysaccharide
  • Platelia Aspergillus
  • Platelia Aspergillus Ag
  • Platelia Aspergillus Galactomannan
  • serum aspergillus galactomannan
Aspergillus Galactomannan Antigen by EIA, Serum