Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
PCR testing is preferred for diagnosis of acute infection. Detect neutralizing antibodies to coxsackie B virus.
MnemonicUnique test identifier.
COX B
MethodologyProcess(es) used to perform the test.
Semi-Quantitative Serum Neutralization
PerformedDays of the week the test is performed.
Mon- Fri
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
6-9 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum Separator Tube (SST) or Plain Red.
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Remarks
Mark specimens plainly as "acute" or "convalescent."
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Coxsackie B1: Less than 1:10 Coxsackie B2: Less than 1:10 Coxsackie B3: Less than 1:10 Coxsackie B4: Less than 1:10 Coxsackie B5: Less than 1:10 Coxsackie B6: Less than 1:10
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
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