PCR testing is preferred for diagnosis of acute infection. Detect neutralizing antibodies to echovirus types 6, 7, 9, 11, and 30.
Semi-Quantitative Serum Neutralization
New York DOH Approval Status
Serum Separator Tube (SST) or Plain Red.
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples.
CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Mark samples plainly as "acute" or "convalescent."
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Echovirus 6: Less than 1:10
Echovirus 7: Less than 1:10
Echovirus 9: Less than 1:10
Echovirus 11: Less than 1:10
Echovirus 30: Less than 1:10
Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.
|Component Test Code*||Component Chart Name||LOINC|
|0065114||Echovirus Antibody Type 6||5144-1|
|0065116||Echovirus Antibody Type 7||41492-0|
|0065117||Echovirus Antibody Type 11||41489-6|
|0065119||Echovirus Antibody Type 30||41491-2|
|0065132||Echovirus Antibody Type 9||5146-6|
- Echovirus Ab Panel
- Echovirus Antibodies
- Echovirus antibody profile, IgG, IgM
- Echovirus Antibody, Neutralization