Ordering Recommendation

PCR testing is preferred for diagnosis of acute infection. Detect neutralizing antibodies to echovirus types 6, 7, 9, 11, and 30.

Mnemonic
ECHO
Methodology

Semi-Quantitative Serum Neutralization

Performed

Mon-Fri

Reported

6-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Remarks

Mark samples plainly as "acute" or "convalescent."

Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Echovirus 6:  Less than 1:10
Echovirus 7:  Less than 1:10
Echovirus 9:  Less than 1:10
Echovirus 11: Less than 1:10
Echovirus 30: Less than 1:10

Interpretive Data

Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection.  Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.

Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

86658 x5

Components
Component Test Code* Component Chart Name LOINC
0065114 Echovirus Antibody Type 6 5144-1
0065116 Echovirus Antibody Type 7 41492-0
0065117 Echovirus Antibody Type 11 41489-6
0065119 Echovirus Antibody Type 30 41491-2
0065132 Echovirus Antibody Type 9 5146-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Echovirus Ab Panel
  • Echovirus Antibodies
  • Echovirus antibody profile, IgG, IgM
  • Echovirus Antibody, Neutralization
  • Enterovirus
Echovirus Antibodies